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Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, has globally infected more than 639 million individuals and claimed over 6.6 million lives. Despite the rapid commencement of COVID-19 vaccination programs in most countries across the world, the virus has remained in circulation.
Sahlgrenska University Hospital Receptor Binding Domain Coronavirus Disease Covid 19 Ars Cov 2 B Cell Covid 19

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.
Juan Gaertner Lab Diagnostics Automation Lab Diagnostics Automation Industry Memoryb Cells Memoryt Cells Induced Infection Show Different Dynamics

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.
West Nile Zika Virus B Cell West Nile Virus Yellow Fever

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COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

A study published in the journal Frontiers in Immunology describes that the third booster dose of coronavirus disease 2019 (COVID-19) effectively induces an immune response against immunologically more fit variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the immunity induced by the booster vaccination is transient and gradually declines over time.
Coronavirus Disease Covid 19 Immune Response B Cell Ars Cov 2 Evere Acute Respiratory Evere Acute Respiratory Syndrome

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