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Transcripts for BBCNEWS BBC News 20240604 17:26:00

and i saw southgate to continue. absolutely, and i saw the southgate to continue. absolutely, and i saw the pain southgate to continue. absolutely, and i saw the pain written - southgate to continue. absolutely, and i saw the pain written across i and i saw the pain written across your face, and i saw the pain written across yourface, iam and i saw the pain written across yourface, i am sorry! thank you and i saw the pain written across your face, i am sorry! thank you for bringing us the update. a world first now a teenage girl s incurable cancer has been cleared from her body using a revolutionary new type of medicine. all other treatments for alyssa s leukaemia had failed. the ground breaking treatment is known as base editing . it involves making genetic changes to donor cells, enabling them to attack her cancer. 0ur medical editor, fergus walsh, reports. iwon! no, you didn t! yes, idid. i didn t feel like i wanted to give up. it s not the person who i am. no, it don t count

Cancer
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Leukaemia

Transcripts for BBCNEWS BBC News 20240604 18:05:00

the whole experience has brought me so much closer to my family. alyssa is back at home in leicester thanks to a pioneering new cancer therapy. all other treatment options for her leukaemia had failed. breathe in and breathe out. . thank you, that s a good one. so in may she received a world first therapy. i know that i ve helped other children as well, that other children might be able to get cured because of the research that i ve been part in. it is extremely exciting, - so obviously this is a new field i in medicine and it s fascinating i that we can redirect the immune system to fight cancer. alyssa s immune system couldn t clear her cancer, so she was given donor cells which had been tweaked using a new technique called base editing. in the lab three precise changes were made to the cells dna, and they were then armed

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Transcripts for BBCNEWS BBC News 20240604 14:14:00

and i think that s a revolution in our field. alyssa s immune system couldn t clear her cancer, so she was given donor cells, which had been tweaked using a new technique called base editing. in the lab, three precise changes were made to the cells dna, and they were then armed to fight her cancer. base editing is part of a genetic revolution, which is transforming our understanding of human biology. it is an incredibly precise tool with huge potential to treat and possibly cure a range of diseases, especially disorders of the blood. ten children with t cell leukaemia will have the treatment as part of a clinical trial. it s a very fast moving area of science. there s enormous amounts of innovation going on in terms of how we can use these new tools to manipulate and change bits of dna. and our applications

Cancer
Base-editing
Procedure-alyssa
Donor-cells
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Immune-system
Revolution
Technique
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Changes
Cells-dna

Transcripts for BBCNEWS BBC News 20240604 15:12:00

oh, this one s hard. the whole experience has brought me so much closer with my family. alyssa is back home in leicester thanks to a pioneering new cancer therapy. all other treatment options for her leukaemia had failed. breathe in and breathe out. thank you. that s a good one. so, in may, she received a world first therapy. i know that i ve helped other children as well, that other children might be able to get cured because of the research that i ve been part in. it is extremely exciting. so, obviously, this is a new field in medicine and it s fascinating that we can redirect the immune system to fight cancer. alyssa s immune system couldn t clear her cancer, so she was given donor cell, which had been tweaked using a new technique called base editing . in the lab, three precise changes

One
Procedure-alyssa
Leukaemia
Thanks
Family
Cancer-therapy
Treatment-options
Hard
Experience
Leicester
Children
World-first-therapy

Transcripts for BBCNEWS BBC News 20240604 17:27:00

a world first therapy. it is extremely exciting. so obviously, this is a new field in medicine and it s fascinating that we can redirect the immune system to fight cancer. and i think that s a revolution in our field. alyssa s immune system couldn t clear her cancer, so she was given donor cells, which had been tweaked using a new technique called base editing. in the lab, three precise changes were made to the cells dna, and they were then armed to fight her cancer. base editing is part of a genetic revolution which is transforming our understanding of human biology. it is an incredibly precise tool with huge potential to treat and possibly cure a range of diseases, especially disorders of the blood. ten children with t cell leukaemia will have the treatment as part of a clinical trial.

Cancer
Revolution
Field
Medicine
Immune-system
World-first-therapy
Procedure-alyssa
Base-editing
Donor-cells
Changes
Technique
Lab

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