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Modifying Memories Depends on Initial Learning, Hippocampal Stars Indicate

Scientists have identified a molecular mechanism that renders memories flexible. Cognitive flexibility is very important in adapting to a changing environment. The findings lay the foundation for research on how to restore cognitive flexibility with age or in diseases such as autism and schizophrenia. The authors showed that cognitive flexibility is determined at the time of initial learning which refutes previous theories that proposed synaptic plasticity only occurs after memory formation.
Taejon Gwangyoksi South Korea Yulong Li C Justin Lee Wuhyun Koh Institute For Basic Science

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