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The COVID-19 pandemic and resulting public health measures have had significant impacts on daily life, including shifts in health behaviours which contribute to weight gain and may increase subsequent risk of chronic diseases such as cancer. Using OncoSim, a web-based microsimulation tool, we estimated the future burden of cancer in Canada by incorporating data on unintentional weight gain among adults during the first year of the COVID-19 pandemic. Population impact measures were estimated until 2042, assuming a 12-year latency period. We estimated 12,160 excess cancer cases and 4,567 excess cancer deaths by 2042 due to COVID-19 related weight gain. The largest estimated impacts were observed for endometrial, kidney and liver cancers among women, with potential impact fractions (PIF) of 2.87%, 1.67% and 1.30%, respectively. For men, the largest mean PIFs were observed for esophageal (2.48%), kidney (1.85%) and liver (1.47%) cancers. Changes in health behavior during the COVID-19 pande

United statesUnited kingdomBader eddeenCanadian community healthCanadian perspectives survey seriesCanj public healthCanadian partnership against cancerPrev med public healthUniversity of british columbiaJ pub healthBc cancer research centreAssociation between alcohol intakeCorrelations with health behaviorCanadian partnership against cancer oncosimMichael smith foundation for health researchWardlej making health habitual