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Study investigates the antigenic and viral receptor-binding properties of major Omicron BA 2 75 subvariants

Researchers in the US examined the neutralization evasion and receptor affinity properties of SARS-CoV-2 Omicron BA.2.75 sub-variants.

United statesMichal bednarek shutterstockIndustry focusCoronavirus disease covid 19Binding affinityArs cov 2Evere acute respiratoryEvere acute respiratory syndrome

Research highlights the potential risk of secondary SARS-CoV-2 transmission from wild rats

In a recent study published in the journal mBio, researchers in the United States evaluated rat exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC).

New yorkUnited statesHong kongHolger kirkDelta alphafinallyNew york cityNorway ratsImage creditGenomics industry focusCoronavirus disease covid 19Ars cov 2Amino acidBinding affinityEvere acute respiratoryEvere acute respiratory syndromeSpike protein

Engineering epitope scaffolds of conserved regions of SARS-CoV-2 spike

In a recent study posted to the bioRxiv preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

Beta covsEngineered immunogensExpose conserved epitopes targetedBroad coronavirusImage creditCorona borealisIndustry focusCoronavirus disease covid 19Ars cov 2Binding affinityEvere acute respiratoryEvere acute respiratory syndromeSpike protein

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Researchers assessed the impact of a single-dose dendritic cell vaccine candidate on immune responses against SARS-CoV-2.

C adjuvanted clecDiscovery industry focusCoronavirus disease covid 19Ars cov 2Binding affinityDendritic cellEvere acute respiratoryEvere acute respiratory syndrome

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

Viacheslav lopatin shutterstockVaccine improves immunity against viralImage creditIndustry focusCoronavirus disease covid 19Ars cov 2B cellBinding affinityCovid 19Evere acute respiratoryEvere acute respiratory syndromeSpike proteinWeight loss

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