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Novel approach to interrogate tissue-specific protein-protein interactions

Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from the...
Xiang David Li Li Ka Shing Xiang David Chaogu Zheng School Of Biomedical Sciences Proceedings Of The National Academy Sciences

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Cell-targeting technology can isolate neuronal subpopulations and link them to behavioral states

As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel. This led scientists at St. Jude Childrens Research Hospital to create a tool to improve the ease and accuracy with which investigators can study specific subpopulations of cells.
Alex Hughes Lindsay Schwarz Alexc Hughes Jude Graduate School Of Biomedical Sciences Jude Department Of Developmental Neurobiology Allen Institute For Brain Science

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