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tenderness and pain in psoriatic arthritis. and no routine blood tests required. dont use if youre allergic to otezla. otezla can cause serious allergic reactions. it may cause severe diarrhea, nausea, or vomiting. otezla is associated with an increased risk of depression. tell your doctor if you have a history of depression or suicidal thoughts or if these feelings develop. some people taking otezla reported weight loss. your doctor should monitor your weight and may stop treatment. u...