Immune cell patterns have been discovered within tumours that can help predict if patients with kidney cancer will respond to immunotherapy, as part of a study co-led by researchers at UCL, the Francis Crick Institute and The Royal Marsden NHS Founda
Read Time:
Researchers from the Francis Crick Institute, Royal Marsden, UCL and Cruces University Hospital have found that cells from different parts of kidney tumours behave differently, and surprisingly, cells within the centre of a tumour are the most aggressive and have the highest chance of spreading around the body.
Cancers can spread to other parts of the body, with cells taking hold as secondary tumours which make the disease much harder to treat. Understanding the mechanics of this spread, a process called metastasis, could lead to new treatments that block this migration.
In their multidisciplinary study published today (17 May) in Nature Ecology and Evolution, scientists led by the Litchfield lab at UCL and the Turajlic, Swanton, and Bates labs at the Crick, analysed 756 cancer biopsy samples from different regions within tumours from the TRACERx Renal study.
Researchers from the Francis Crick Institute, Royal Marsden, UCL and Cruces University Hospital have found that cells from different parts of kidney tumours behave differently, and surprisingly, cells within the centre of a tumour are the most aggressive and have the highest chance of spreading around the body.
Cells from different parts of kidney tumours behave differently and those within the centre are the most aggressive and have the highest chance of spreading around the body, a new study has found.
Cancers can spread to other parts of the body, with cells taking hold as secondary tumours, making the disease much harder to treat.
Understanding the mechanics of this spread, a process called metastasis, could lead to new treatments that block this migration.
Scientists led by the Litchfield lab at UCL and the Turajlic, Swanton, and Bates labs at the the Francis Crick Institute analysed 756 cancer biopsy samples from different regions within tumours from the TRACERx Renal study.
Cells from centre of tumours most likely to spread around body – study thisislancashire.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thisislancashire.co.uk Daily Mail and Mail on Sunday newspapers.