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First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure

AB-1002 is an investigational gene therapy for the treatment of adults with non-ischemic cardiomyopathy and New York Heart Association (NYHA) Class III heart failure symptoms1GenePHIT is a clinical trial to evaluate the safety and efficacy of the one-time administration of AB-1002 and will include the largest number...
University Of North Carolina North Carolina United States Research Triangle Park City Of United Kingdom

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FDA Approves Intravenous Iron Replacement Therapy for Heart Failure Patients

Daiichi Sankyo, Inc. and American Regent, Inc., a Daiichi Sankyo Group company, have announced that the U.S. Food and Drug Administration (FDA) approved INJECTAFER (ferric carboxymaltose injection) for the treatment of iron deficiency in adult patients with heart failure categorized as New York Heart Association class II/III to improve exercise capacity. The company reported that with this approval, INJECTAFER is now the first and only intravenous (IV) iron replacement therapy indicated for ad...
United States Ravi Tayi American Heart Association Daiichi Sankyo Group Daiichi Sankyo Inc European Union

Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial

An intensive treatment strategy of rapid up-titration of guideline-directed medication and close follow-up after an acute heart failure admission was readily accepted by patients because it reduced symptoms, improved quality of life, and reduced the risk of 180-day all-cause death or heart failure readmission compared with usual care.
Coll Cardiol Van Spall Heart Failure Association European Society Of Cardiology Cardiology Society Of India Failure Long Term

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