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PARAGLIDE-HF Offers Further Insight into Sacubitril/Valsartan in Heart Failure with Elevated EF

Presented at ESC HFA 2023, results of PARAGLIDE-HF detail the effects of sacubitril/valsartan on NT-proBNP and multiple clinical outcomes, relative to valsartan alone, in patients with HFmrEF or HFpEF.

Carlj lavieHectoro venturaMandeepr mehraSacubitril valsartanEuropean society of cardiologyDuke university medical center robert mentzHeart failure associationJournal of the american college cardiologyDuke university medical centerRobert mentzEuropean societyFailure associationAmerican college

Obesity Paradox in AF Challenged as Mortality Climbs With BMI

Mortality rose with body mass index in patients with new atrial fibrillation in a GARFIELD-AF analysis, which also examined BMI effects on bleeding with NOACs vs vitamin-K antagonists.

United kingdom generalUnited kingdomUnited statesNew orleansCarlj lavieBritish heart foundationUniversity of oxfordVascular instituteUniversity of queensland school medicineChristian fielder cammRoyal berkshireJohn ochsner heartQueensland schoolHazard ratiosBelow riskBritish heart

Cardiorespiratory Fitness Is Key to Longevity, Regardless of Age, Sex, and Race

Instead of asking patients how much they exercise, Claudio Gil Araújo suggests focusing on their fitness level.

United statesRio de janeiroEstado do rioCarlj laviePeter kokkinosPhd washington dc va medical centerMd ochsner clinical schoolUniversity of queensland school medicineJournal of the american college cardiologyVeterans affairsClaudio gil araExercise medicine clinicAmerican collegeAfrican americansNative americansOchsner clinical school

Cardiorespiratory Fitness Key to Longevity for All?

Risk for all-cause mortality was four times greater for US veterans with lowest vs those with highest cardiorespiratory fitness levels, regardless of age, sex, or race, observational data suggest.

United statesRio de janeiroEstado do rioRutgers universityNew jerseyNew brunswickCarlj lavieColl cardiolPeter kokkinosAmerican heart associationOchsner healthJournal of the american college cardiologyHealth outcomes studyVa medical centerAmerican collegeAfrican american

Nordic walking improves functional capacity in people with heart disease

Nordic walking improves functional capacity in people with heart disease
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United statesCarlj lavieTasuku teradaJenniferl reedOchsner clinical schoolUniversity of queensland school medicineVascular instituteFaculty of health sciencesDepartment of cardiovascular diseasesUniversity of ottawaCardiovascular health labSchool of human kineticsDivision of cardiac preventionUniversity of ottawa heart instituteCanadian journalExercise physiology