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Horse-derived hyperimmune serum may help in fight against Covid-19, study finds

Dark energy survey releases most precise look at the universe s evolution

In 29 new scientific papers, the Dark Energy Survey examines the largest-ever maps of galaxy distribution and shapes, extending more than 7 billion light-years across the Universe. The extraordinarily precise analysis, which includes data from the survey s first three years, contributes to the most powerful test of the current best model of the Universe, the standard cosmological model. However, hints remain from earlier DES data and other experiments that matter in the Universe today is a few percent less clumpy than predicted.

Phase transition inside the nucleus provides oncogenic function to mutant p53 in cancer

 E-Mail IMAGE: Pathway of mutant p53 from liquid droplets to gel-like and solid-like (amyloid) states, in vitro and in cell. view more  Credit: Guilherme de Oliveira Cancer has been recently shown to be affected by protein clusters, particularly by the aggregation of mutant variants of the tumor suppressor protein p53, which are present in more than half of malignant tumors. However, how the aggregates are formed is not yet fully understood. The understanding of this process is expected to provide new therapeutic tools able to prevent proteins to clump and cancer progression. In Brazil, researchers at the Federal University of Rio de Janeiro have identified a key mechanism behind the mutant p53 aggregation process, linked to cancer pathology, opening new paths for the development of novels drugs against the disease.

31% of dogs and 40% of cats tested positive to COVID-19 after owners diagnoses

Article Title: Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil Funding: MMS: This study was supported by CGLab/MoH (General Laboratories Coordination of Brazilian Ministry of Health), CVSLR/FIOCRUZ (Coordination of Health Surveillance and Reference Laboratories of Oswaldo Cruz Foundation), The National Council for Scientific and Technological Development (CNPq) COVID-19 MCTI 402457/2020-0, INOVA VPPCB-005-FIO-20-2-69, and Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ) E26/210.196/2020. Competing Interests: The authors have declared that no competing interests exist.

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