Page 4 - Cell Biol News Today

Researchers found that the activity of a particular enzyme in the blood was significantly higher in horses with lymphoma.

Stacy Blain A breast cancer researcher at SUNY Downstate in Brooklyn has sued the university for sex discrimination and retaliation after an institutional investigation found she committed research misconduct.  Stacy Blain, an associate professor in the departments of pediatrics and cell biology at Downstate, has alleged that the university violated the Equal Pay Act by…

If you haven’t heard about spermadine for longevity already, then it’s name you’ll become more familiar with after reading this article

Clinical signs of cancer in horses can be vague, and confirming a diagnosis in systemic cases can be challenging.

Although targeting BRAF mutants with RAF inhibitors has achieved promising outcomes in cancer therapy, drug resistance remains a remarkable challenge, and underlying molecular mechanisms are not fully understood. Here, we characterized a previously unknown group of oncogenic BRAF mutants with in-frame insertions (LLRins506 or VLRins506) of αC-β4 loop. Using structure modeling and molecular dynamics simulation, we found that these insertions formed a large hydrophobic network that stabilizes R-...

Mechanical strain induces remodeling of the actin cytoskeleton, which is energetically costly. Salvi et al. uncovered a pathway that coupled mechanical strain to nutrient uptake. In MCF-10A breast cancer cells or MDCK epithelial cells, mechanical strain induced glucose uptake through the glucose transporter GLUT1 and increased the localization of GLUT1 at cell-cell junctions. GLUT1 bound to the cell-cell junction protein E-cadherin in MDCK cells in two- or three-dimensional culture. When expos...

DGAP-News: Atriva Therapeutics GmbH: Atriva Therapeutics to Speed up Development of COVID-19 Drug with Federal Funding Atriva Therapeutics to Speed up Development of COVID-19 Drug with Federal Funding 21.04.2021 / 16:03 Atriva Therapeutics to Speed up Development of COVID-19 Drug with Federal Funding German Federal Ministry of Education and Research (BMBF) awards Atriva up to €11.4 million for the clinical development of a drug to treat COVID-19 Product candidate ATR-002 could help hospit...

DGAP-News: Atriva Therapeutics GmbH: Atriva Therapeutics Announces Changes to Management Atriva Therapeutics Announces Changes to Management 13.04.2021 / 09:30 Atriva Therapeutics Announces Changes to Management - Olaf Althaus appointed Chief Financial Officer - Stephan Stenglein, M.D., recently joined as Chief Medical Officer - Proven track record and 20+ years of experience in their respective fields of expertise Tübingen (Germany), April 13, 2021 - Atriva Therapeutics GmbH, a biopharmaceu...

Sun, 18 Oct 2020 19:56 UTC Since I started medical school in 1976, until 2020, I have heard the dogma that viral diseases are not treatable (with some exceptions such as antivirals for HIV/AIDS), certainly not with antimicrobials. My older son, a newly minted general surgeon, was educated much more recently, but with the same misunderstanding. Since viral diseases are not treatable, our only weapon is vaccination. A friend who spent his life as an academic university physician retiring in 2016...

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages. However, detailed analysis in...