Cell Census Network News Today

Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA variants in the mouse and human brain, helping neuroscientists understand how the brain develops and functions.

Despite all our cells sharing the same DNA, there are thousands of different cell types in the human brain, each with a unique structure and function. One longstanding problem in neuroscience is determining how genes are switched on and off to form t

For the first time, an international team of researchers has created a full-cell atlas of a whole mammalian brain. This atlas serves as a map of the mouse

Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.

Divergence of cis-regulatory elements drives species-specific traits1, but how this manifests in the evolution of the neocortex at the molecular and cellular level remains unclear. Here we investigated the gene regulatory programs in the primary motor cortex of human, macaque, marmoset and mouse using single-cell multiomics assays, generating gene expression, chromatin accessibility, DNA methylome and chromosomal conformation profiles from a total of over 200,000 cells. From these data, we show ...

In a huge collaborative effort, millions of cells in the mouse brain have been mapped in detail. Two scientists examine the resulting wealth of insights into gene regulation in brain cells, neuronal connections and how our own brains evolved. Transcriptomic and epigenomic data from millions of mouse brain cells.

<p>For the first time ever, an international team of researchers has created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells. The findings were funded by <a href="https://braininitiative.nih.gov/">the National Institutes of Health’s<em> Brain Research Through Adv...

News and commentary from the world of neurology and neuroscience

Scientists have published a new atlas of a primate brain with single-cell resolution.

Examining the human brain at the cellular level in more detail than ever before, scientists have identified an enormous array of cell types \u2014 more than 3,300 \u2014 populating our most complex organ, creating an atlas that may help pinpoint the cellular basis of neurological diseases and facilitate new therapeutics.