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Existing drug could be repurposed to treat type 1 diabetes, study suggests

Type 1 diabetes is an autoimmune disease that causes the body's immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing the missing insulin with injections which, though effective, can be expensive and burdensome.
Lily Ramsey Saraha Tersey Ernestos Nakayasu Raghu Mirmira Susanm Perkins Emilyk Sims

PROTECT: Teplizumab Preserves Beta-Cell Function in Newly Diagnosed Type 1 Diabetes

In the PROTECT trial, teplizumab preserved β-cell function in newly diagnosed type 1 diabetes patients, slowing the decline of C-peptide levels, but key secondary endpoints, such as time in range and HbA1c, showed numerical trends without statistical significance.
United States Kevan Herold Leonard Thompson Yale School Of Medicine Kevin Herold Drug Administration Medicine At Yale School Of

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Panbela Announces Poster Presentation at Immunology of Diabetes Society Meeting: Evaluating the Potential of CPP-1X (Eflornithine) in Recent Onset Type 1 Diabetes

MINNEAPOLIS, June 01, 2023 -- Panbela Therapeutics, Inc. , a clinical stage biopharmaceutical company developing disruptive therapeutics for the treatment of patients with urgent unmet medical... | June 1, 2023
United States Raghavendra Mirmira Tammy Groene Jenniferk Simpson Globenewswire Inc Nasdaq Stock Market

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