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Parkinson's disease drug ropinirole safely sl

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms and providing supportive care. Reporting June 1 in the journal Cell Stem Cell, researchers from Japan show in an early clinical trial that the Parkinson’s disease drug ropinirole is safe to use in ALS patients and delayed disease progression by 27.9 weeks on a...
Lou Gehrig Satoru Morimoto Hideyuki Okano Japan Society For The Promotion Of Science Japanese Ministry Of Health Labor Okasan Kato Foundation Research Grant

Deep sea surveys detect over five thousand ne

There is a massive, mineral-rich region in the Pacific Ocean—about twice the size of India—called the Clarion-Clipperton Zone (CCZ), which has already been divided up and assigned to companies for future deep-sea mining. To better understand what may be at risk once companies start mining, a team of biologists has built the first “CCZ checklist” by compiling all the species records from previous research expeditions to the region. Their estimates of the species diversity of the CCZ, publ...
United Kingdom City Of Pacific Ocean Muriel Rabone Samuel Bond Method Of Research

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Elucidating the mysteries of enzyme evolution

Professor Nicolas Doucet and his team at Institut national de la recherche scientifique (INRS) made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work, published in the journal Structure, points to potential applications in health, including the development of new drugs to treat serious diseases such as cancer or to counter antibiotic resistance.
United States Purva Prashant Bhojane David Bernard Armand Frappier Sant Elizabethe Howell Chitra Narayanan

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