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Inhaled vaccine induces fast, strong immune response in mice and non-human primates

 E-Mail Researchers demonstrate in a proof-of-concept study that a phage-based inhalation delivery system for vaccines generates potent antibody responses in mice and non-human primates, without causing lung damage. The findings suggest that a safe and effective lung delivery system could one day be used for vaccines and therapeutics against respiratory diseases. The results appear December 10 in the journal Med. "This translational strategy potentially enables more effective delivery of ther...
United States Renata Pasqualini Cancer Center Support Gillson Longenbaugh Foundation Rutgers Cancer Institute Of New Jersey University Of New Mexico Comprehensive Cancer Center

A gene from ancient bacteria helps ticks spread Lyme disease

 E-Mail IMAGE: This photo shows a tick on a blade of grass, waiting for passing prey. view more  Credit: Matt Pinski One of the reasons ticks spread Lyme disease so well goes back to a unique evolutionary event. Researchers reporting in the journal Cell on December 10 have discovered that an antibacterial enzyme in ticks, Dae2, protects them from bacteria found on human skin, while still allowing them to harbor Borrelia burgdorferi, the bacterium that causes Lyme disease. Ticks acquire...
United Kingdom Seemay Chou Chan Zuckerberg Biohub Research Councils United Kingdom National Institutes Of Health University Of California San Francisco

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