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Public Release: 1-Sep-2015 Statin side effects linked to off-target reaction in muscle mitochondria Cell Press   Statin-induced myopathies are the most common side effects of these widely used cholesterol-lowering drugs, affecting millions of patients. Schirris et al. identified the Qo site of mitochondrial complex III as off-target of statin lactones and show possible mechanisms for…

Sometimes they produce it, too | Science & technology

The DEAL Consortium, representing the German research institutions, and Elsevier,a global leader in scientific information and data analytics, are delighted to announce a transformative open access agreement for Germany. The landmark five-year agreement, signed on 1 September by Elsevier and the DEAL operating entity, MPDL Services gGmbH (MPDLS), is set to run until the end of 2028 and is designed to make a large part of German research openly accessible worldwide.

Photo Illustration by Kelly Caminero / The Daily Beast / GettyH.G. Wells introduced much of the world to scientifically engineered human-animal hybrids in his novel The Island of Doctor Moreau. While the procedure is portrayed as a gruesome aberration of nature carried out by a sinister mad scientist, mixing the parts and cells of species could actually help address some of the most pressing medical issues of our time, including the organ donation shortage.In a study published Thursday in the jo

The breakthrough could help alleviate the dire organ transplant shortage.

Lengthy talks for opt-in read-and-publish deal, worth about €35 million a year, reached agreement as publisher warmed to open access and people involved in negotiations changed, consortium says 

Although about half of people go through menopause, less than 15% of them receive effective treatment for their symptoms. Treatment options for people experiencing irritating or severe menopause symptoms are often under researched, and some have questionable efficacy, or cause harmful side effects. In a comprehensive review publishing in the journal Cell on September 6, a team of world-renowned menopause experts summarizes what we know about menopause, calls for more research into the timeline a...

The Projekt DEAL program inks its third major research-publishing agreement, as Elsevier signs a five-year transformative agreement.

From the blog of Jennifer Laszlo Mizrahi at The Times of Israel

Scientists at Rice University in Houston, Texas have developed a fabric-based wearable device that “taps” a user’s wrist with pressurized air, silently helping them navigate to their destination. The study, published August 29 in the journal Device, demonstrated that users correctly interpreted which direction the device was telling them to go an average of 87% of the time. Since the wearable embeds most of its control system within the fabric itself, using air instead of electronics, it c...