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Worm genetics reveal important pathways for s

Researchers from the University of Tsukuba have found that, in worms, protein-regulating pathways in the body help to control sleep. Moreover, some of the worm-related findings were replicated in mice, indicating that these peripheral pathways are also important in mammals. These results add to our growing knowledge around sleep regulation and may inform therapies to reduce human sleep disturbances in the future.
Yu Hayashi Department Of Biological Sciences Asahi Glass Foundation University Of Tsukuba Astellas Foundation For Research On Metabolic Disorders International Institute For Integrative Sleep Medicine

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Worm genetics reveals key pathways for sleep regulation: Study

Washington, June 7: Although the brain is thought to manage sleep regulation--how much, when, and how much sleep occurs--sleep deprivation affects the body, and signals from the body can affect sleep. The mechanisms by which the body regulates sleep, on the other hand, remain largely unknown. According to a recent study published in Cell Reports, sleep in worms is regulated by the body via cellular pathways that maintain optimal protein function, from synthesis to breakdown.
United States Yu Hayashi Saif Ali Khan University Of Tsukuba Cell Reports Professor Yu Hayashi

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