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Groundbreaking USC-Led Study Introduces Improved Method for Cultivating Kidney Filtration System Cells

In a new study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney’s filtration system, the nephrons. NPCs hold immense promise for understandin
Xi Chen Pedro Medina Zhenqing Liu Matthewe Thornton Tianyuan Xiang Brendanh Grubbs

USC Scientists Rewrite Kidney Research With Groundbreaking Cell Cultivation

Researchers at USC have advanced kidney research by developing a new method to cultivate nephron progenitor cells from human stem cells. This method simplifies the process and enhances applications in disease modeling and drug discovery. In a new study published today in Cell Stem Cell, USC scien
Xi Chen Connorc Fausto Arielc Vonk Rianak Parvez Brendanh Grubbs Yidan Li

Mini Kidneys Uncover Big Advances in Polycystic Kidney Disease Research

NTU Singapore's groundbreaking study on 'mini kidneys' offers new hope for treating polycystic kidney disease, with minoxidil emerging as a promising therapy. Scientists at Nanyang Technological University, Singapore (NTU Singapore) have successfully grown ‘mini kidneys’ in the lab and grafted th
National University Hospital Singapore General Khoo Teck Puat Xia Yun Kar Hui Zhang Chao

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Shaking tiny clusters of brain cells, scienti

<p>Clinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact sports and military services. A new study, published April 4 in the journal <em>Cell Stem Cell</em>, may offer new clues to better solutions. Scientists found a protein, TDP-43, that appears to drive nerve damage right after injury. Moreover, blocking a certain cell surface protein can correct faulty TDP-43 and curb nerve death in mouse and huma...
United States Justin Ichida University Of Southern California Method Of Research Cell Stem Stem Cell

Researchers Gain Enhanced Insight into Stem Cell Aging in the Brain with New Tool

Researchers can use the light naturally thrown off by biological specimens to better study the different states of stem cells in the nervous system, thanks to a tool developed at the University of Wisconsin–Madison, brightening their chances for stud
Darcie Moore Melissa Skala Colin Crist Darcie Moore Melissa Skala Regenerative Medicine Center University Of Wisconsin

ROCK And The Death Dance Of Isolated Human Embryonic Stem Cells

Researchers at the RIKEN Center for Developmental Biology say they have unraveled the mystery of why human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells undergo apoptosis (programmed cell death) when cultured in isolation, a discovery that promises new hope to sufferers of debilitating degenerative diseases.
Developmental Biology Molecular Pathway Cell State Responsible Dissociation Induced Apoptosis Human Pluripotent Stem Cells Cell Stem

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