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Heme is an essential part of the protein hemoglobin, which colors human blood red. Heme also is crucial for cytochrome proteins, which power the cell. Humans, animals, plants and bacteria all use heme.

Scientists at Washington University in St. Louis described for the first time the structure of a bifunctional protein, called CcsBA, that transports

Scientists at Washington University in St. Louis described for the first time the structure of a bifunctional protein which transports heme and attaches it to cytochromes. The study led by Robert Kranz, professor of biology in Arts & Sciences, captured two conformational states, allowing scientists to characterize the enzyme mechanisms.

Heme is an essential part of the protein hemoglobin, which colors human blood red. Heme also is crucial for cytochrome proteins, which power the cell

Close Maurice Gaubatz is founder and CEO of Pyxant Labs, a Colorado Springs-based research lab that specializes in biological testing for pharmaceutical manufacturers. French private equity firm ArchiMed is acquiring Pyxant and two other companies next month. JERILEE BENNETT, THE GAZETTE FILE

A newly identified coronavirus may not pose a serious threat, but the finding highlights the need to monitor animal viruses more proactively, scientists say.

COVID-19 Can Kill Heart Cells and Interfere With Contraction Study reveals details of how coronavirus infects the heart and heart damages cardio myocytes A study from Washington University School of Medicine in St. Louis provides evidence that the coronavirus can invade and replicate inside heart muscle cells, causing cell death and interfering with heart muscle contraction. The image of engineered heart tissue shows human heart muscle cells (red) infected with COVID-19 (SARS-CoV-2) (green). Im...

A new study provides evidence that COVID-19 patients’ heart damage results from the virus invading and replicating inside heart muscle cells, leading to cell death and interfering with heart muscle contraction. The researchers used stem cells to engineer heart tissue that models the human infection and could help in studying the disease and developing possible therapies. “Early on in the pandemic, we had evidence that this coronavirus can cause heart failure or cardiac injury in generally h...

Neuronal Imaging for Central Nervous Systems Drugs Sponsored by Photon etcJul 27 2018 The Biosimulation and Imaging platform for new Central Nervous System drugs (BICNSD) is a 3 year project for the validation and development of a unique service based on biosimulation and imaging using two synergistic platforms. This will boost drug development and discovery through tracking drug candidates’ actions at molecular and subcellular levels and having a greater understanding of Cent...

 E-Mail IMAGE: Shown is a transmission electron microscope image of exosomes purified from fluid from the lungs of a patient with COPD. A new study from Washington University School of Medicine in... view more  Credit: Deb Steinberg/WU Center for Cellular Imaging Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19, have proven difficult to treat. Current therapies reduce symptoms and do little to stop such diseases from continuing to damage the lungs. Much res...