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Bubonic plague, or the "Black Death" placed significantly selective pressure on humans, changing the frequency of certain immune-related genes and affecting our susceptibility to modern diseases.

City ofUnited kingdomLuis barreiroG brian goldingSharonn dewitteChristiane demeureInstitut pasteurMariai patinoAlison caldwellMatthias steinrJavier pizarro cerdaXiaoheng chengHendrik poinarRebecca redfernAnne dumaineDominique missiakas