Six-hour time-restricted feeding inhibits lung cancer progression and reshapes circadian metabolism | BMC Medicine
Accumulating evidence has suggested an oncogenic effect of diurnal disruption on cancer progression. To test whether targeting circadian rhythm by dietary strategy suppressed lung cancer progression, we adopted 6-h time-restricted feeding (TRF) paradigm to elucidate whether and how TRF impacts lung cancer progression. This study used multiple lung cancer cell lines, two xenograft mouse models, and a chemical-treated mouse lung cancer model. Stable TIM-knockdown and TIM-overexpressing A549 cells ...
United States A Puro Cyagen Biosciences Cyagen Biosciences Lin Yong Sigma Aldrich Ethics Committee Of Chongqing Medical University
Source: biomedcentral.com