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Securing the Future of Lithium Research

How can we enhance our lithium research?

ARECOR AND TRx BIOSCIENCES ESTABLISH RESEARCH COLLABORATION TO DEVELOP ORAL GLP-1 WITH ENHANCED BIOAVAILABILITY

Future Proofing Lithium Pharmacokinetic Research

Future use of a 12-hour standardized lithium serum concentration notation: the first step towards more interpretable scientific literature and the return of the therapeutic importance of lithium.

Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial

Neurosteroid Therapeutics "Offer Great Promise" in Postpartum Depression

Neurosteroid therapeutics could be the solution to provide fast-acting treatment for mothers with postpartum depression.

Lisocabtagene maraleucel in chronic lymphocytic leukaemia and small lymphocytic lymphoma (TRANSCEND CLL 004): a multicentre, open-label, single-arm, phase 1–2 study

Using Collaborative Care to Improve Outcomes for Patients With Schizophrenia and COVID-19

Individuals with schizophrenia have experienced an increase in psychiatric, medical, and treatment risks because of the COVID-19 pandemic.

Biora Therapeutics (BIOR) Announces Bioavailability Results for Oral Delivery of GLP-1 Receptor Agonist

Who really benefits from drug combinations and long titrations for pain? – Authors' reply

We thank Thomas Perry for taking the time to read and respond to our work. In the OPTION-DM trial,1 we included pregabalin rather than gabapentin as pregabalin is a twice-daily drug that made blinded dosing easier for the trial, has 3–4 times faster absorption after oral administration, has dose-dependent predictable plasma concentration, and requires a shorter titration period.2,3 Moreover, there was little rationale in having two drugs with a similar mechanism of action. We disagree with the statement “evidence for dose response from analgesics is tenuous” as some analgesics, such as pregabalin, have dose-dependent efficacy.

Mitochondrial functions of skeletal muscle in sarcopenia

Reviewing the effect of metabolites on mitochondrial functions in the pathogenesis of skeletal muscle aging. Read more