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FDA Grants Clearance for Phase 3 Study of Lisaftoclax in Previously Treated CLL/SLL

The FDA has granted clearance for a global, registrational, phase 3 study examining lisaftoclax in combination with a BTK inhibitor in patients with relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma who received prior treatment with a BTK inhibitor.
Ascentage Pharma Yifan Zhai Chronic Lymphocytic Leukemia Apg 2575 Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma

Earlier-Line Pirtobrutinib Investigation May Alter BTK Inhibitor Sequencing in CLL and MCL

Prioty Islam, MD, MSc, discusses findings from the BRUIN trial, highlights the potential benefits of using noncovalent BTK inhibitors instead of or before covalent BTK inhibitors in patients with MCL or CLL, and previewed ongoing clinical trials investigating this class of agents in earlier treatment lines in these populations.
Memorial Sloan Kettering Cancer Center New York United States Pirtobrutinib Jaypirca Prioty Islam Sloan Kettering Cancer Center

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Going Green: Fleet Of 50 New Cng Midi Buses To Ply On City Streets Soon, ET Auto

Fleet Of 50 New CNG Bus: All buses will be equipped with GPS based Automatic Vehicle Location System (AVLS) connected with Central Control and Command Center for real time monitoring of bus operations. Automatic alert generation and redressal for various city functions like route deviation, schedule adherence system/trip miss system for buses, speed violation are likely to be implemented in its entirely with upgradation of BCLL IT this year.
Madhya Pradesh Automatic Vehicle Location System Central Control Command Center Fleet Of 50 New Cng Bus Entral Control And Command Center

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