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Kite's Car T-cell Therapy Yescarta Demonstrates High Response Rate and Durable Remission in ALYCANTE Study as Initial Treatment for Transplant Ineligible Patients with Relapsed, Refractory Large B-cell Lymphoma

SANTA MONICA - Kite, a Gilead Company , today announced results from the Phase 2 ALYCANTE study, led and sponsored by the French collaborative group LYSA/LYSARC, for use of its chimeric antigen...
Santa Monica United States Foster City Jacquie Ross Frank Neumann Roch Houot

Kite's Car T-cell Therapy Yescarta® Demonstrates High Response Rate and Durable Remission in ALYCANTE Study as Initial Treatment for Transplant Ineligible Patients With Relapsed/Refractory Large B-cell Lymphoma

โ€“ Yescarta Achieved a Complete Metabolic Response of 71% at 3 Months Versus 12% Expected with Historical Standard of Care Controls โ€“ โ€“ Results Published in Nature Medicineโ€“ ...
United States Santa Monica Foster City Frank Neumann Roch Houot Gilead Sciences Inc

From target discovery to clinical drug development with human genetics

The substantial investments in human genetics and genomics made over the past three decades were anticipated to result in many innovative therapies. Here we investigate the extent to which these expectations have been met, excluding cancer treatments. In our search, we identified 40 germline genetic observations that led directly to new targets and subsequently to novel approved therapies for 36 rare and 4 common conditions. The median time between genetic target discovery and drug approval was ...
San Francisco United States Southwest Finland Van Goor Lopes Alves Davey Smith
Source: nature.com

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AstraZeneca: TAGRISSO achieved unprecedented survival in early-stage EGFR-mutated lung cancer, with 88% of patients alive at five years in ADAURA Phase III trial

Treatment with adjuvant TAGRISSO reduced the risk of death by more than half Positive results from the ADAURA Phase III trial showed AstraZeneca's TAGRISSO (osimertinib) demonstrated a statistically
United States United Kingdom Chelsea Ford Le Chevalier Daiichi Sankyo Brendan Mcevoy

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