Job: Scientist in Physical Sciences and Canada Research Chair – Tier 2 in Contrast Agents and Biosensors for Medical Imaging and Image-Guided Therapy (one position) - Sunnybrook Research Institute Toronto, Canada
NSF s mission is to advance the progress of science, a mission accomplished by funding proposals for research and education made by scientists, engineers, and educators from across the country.
A new study by a team of researchers at the Keck School of Medicine, University of Southern California, USA, reports a potentially important therapeutic target in the form of a molecule called GRP78 that promotes the entry and protein production by many viruses. The team's paper has been published in the Journal of Biological Chemistry.
Designer SARS-CoV-2 RBD vaccine produces dramatically improved antibody response in preclinical trials
The importance of computational modeling in the prediction of the course of the ongoing coronavirus disease 2019 (COVID-19) pandemic, as well as evaluating multiple potential drug leads, has never been more clear. Now, a new study describes a set of designer vaccine antigens that may improve vaccine stability as well as enhance the neutralizing antibody response.
The virus causing this pandemic is the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes an asymptomatic or mild infection in the vast majority, but spreads rapidly and extensively to produce a huge caseload in a relatively short period of time. This has led to overwhelming demands on healthcare services in many severely affected countries.
Computational Modeling in Medicine
In the past few decades, information technology has revolutionized the medical industry. The accuracy with which biological systems and interactions can be simulated and data can be gathered have improved exponentially. Computational modeling has provided ever-more sophisticated data for the field of medical research. This article will discuss this subject.
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What is computational modeling?
Computational modeling is used to simulate and study complex systems using computer science, physics, and mathematics. Numerous variables are programmed into the computational model to characterize the system which is being studied. By adjusting these variables alone or in various combinations, the outcome can be observed, providing valuable data for researchers.