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September 7, 2023
DNA double-strand breaks (DSBs) are deleterious lesions that challenge genome integrity. To mitigate this threat, human cells rely on the activity of multiple DNA repair machineries that are tightly regulated throughout the cell cycle1. In interphase, DSBs are mainly repaired by non-homologous end joining and homologous recombination2. However, these pathways are completely inhibited in mitosis3–5, leaving the fate of mitotic DSBs unknown. Here we show that DNA polymerase theta6 (Polθ...
November 30, 2022
The Dragonfly 600 confocal microscope from Andor Technology Ltd. allows users to image live specimens for days without phototoxicity or photobleaching
November 15, 2022
Oxford Instruments Andor has launched Dragonfly 600, further strengthening its renowned confocal microscopy portfolio
January 17, 2022
High-temperature laser-scanning confocal microscopy (HT-LSCM) has proven to be an excellent experimental technique through in situ observations of high temperature phase transformation to study kinetics and morphology using thin disk steel specimens. A 1.0 kW halogen lamp within the elliptical cavity of the HT-LSCM furnace radiates heat and imposes a nonlinear temperature profile across the radius of the steel sample. When exposed at the solid/liquid interface, this local temperature profile det...
December 24, 2021
The BC43 is a benchtop confocal microscope that is a super-compact unit that is rich in features and benefits, making it the ideal microscope for early-stage researchers and experienced microscopists alike.
August 12, 2021
Understand what factors impact the price of a confocal microscope.
April 16, 2021
The topic of peritectic phase transition in steel has been widely studied using various in-situ experimental techniques including visual observation on a surface of a sample in a high temperature microscope and measurement of the thermal response from the bulk of the sample using differential thermal analysis (DTA) and differential scanning calorimetry (DSC). These two different techniques have inherent limitations leading to difficulties in interpretation of the results in the case of complex p...
December 28, 2020
NASA Space Station On-Orbit Status 22 December, 2020 - Physics Phenomena Status Report - Source: SpaceRef NASA Space Station On-Orbit Status 22 December, 2020 - Physics Phenomena. The seven-member Expedition 64 crew, consisting of five astronauts and two cosmonauts, will spend the rest of the year conducting valuable space research aboard the International Space Station. Tuesdays slate of science investigations explored a range of space biology and physics phenomena to benefit hum...