When Waddington meets Helmholtz: EPR-Net for constructing the potential landscapes of complex non-equilibrium systems techxplore.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from techxplore.com Daily Mail and Mail on Sunday newspapers.
Understanding how cell becomes person – with maths miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Developing stem cell-based biotherapies depends crucially on differentiation. At Osaka University in Japan, Masahiro Kino-oka, PhD, professor in the department of biotechnology and director in the research base for cell manufacturability, uses Waddington’s epigenetic landscape to control differentiation of induced pluripotent stem cells (iPSCs) and create homogenous cultures. Although Waddington’s idea is not new, Kino-oka envisions unique advances in iPSC bioprocessing by using this concept.