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Assessing key research trends in virtual learning during the COVID-19 pandemic through a bibliometric analysis of 1595 studies from 589 journals during 2020-21

BioPharma

Five out of every six antibiotics prescribed before an appointment with a Veterans Affairs, or VA, dentist were inconsistent with guidelines, researchers found. “Antibiotic prophylaxis guidelines for dental procedures are lacking,” Katie J. Suda, PharmD, MS, professor of medicine at the University of Pittsburgh, and colleagues wrote in Infection Control & Hospital Epidemiology.

C diff infection Secondary analysis of patients from a postdischarge decolonization trial of methicillin-resistant Staphylococcus aureus (MRSA) carriers found that re-hospitalization for MRSA was associated with extensive exposure to non-MRSA antibiotics and Clostridioides difficile infection (CDI), researchers reported today in Infection Control & Hospital Epidemiology. The CLEAR (Changing Lives to Eradicate Antibiotic Resistance) Trial, conducted from March 2011 through April 2014, found t...

Audit and feedback, prior approval may reduce fluoroquinolone use A study of Veterans Affairs (VA) hospitals found that prospective audit and feedback (PAF) and prior-approval strategies focused on fluoroquinolone use were associated with lower fluoroquinolone prescribing rates, US researchers reported today in Infection Control & Hospital Epidemiology. Despite multiple safety warnings on fluoroquinolones from the Food and Drug Administration and concerns about antibiotic resistance and Clost...

FDA approves Melintas Kimyrsa for skin infections Melinta Therapeutics of Morristown, New Jersey, announced yesterday that the US Food and Drug Administration (FDA) has approved Kimyrsa (oritavancin) for treatment of adult patients with acute bacterial skin and skin-structure infections (ABSSSIs) caused by susceptible gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). Kimyrsa delivers a complete course of the lipoglycopeptide antibiotic oritavancin in a sing...

Stewardship intervention linked to more appropriate ER prescribing A multifaceted intervention implemented in a Japanese emergency department was associated with reduced antibiotic prescribing at discharge and an increase in appropriate prescribing, Japanese researchers reported today in Infection Control and Hospital Epidemiology. In a before-and-after study conducted at a tertiary-care center in Tokyo, hospital researchers compared the average monthly proportion of appropriate antimicrobial ...