The trial "should make complete revascularization the standard of care in MI," and advanced age alone "should no longer be considered a contraindication," said an expert.
Modestly elevated levels of troponin on high-sensitivity assay pointed to impaired perfusion and predicted CV events independent of microvascular dysfunction in patients with nonobstructive CAD.
In patients with a severe stenosis at angiography, routine functional assessment of other intermediate lesions offers little clinical advantage over conservative care, researchers propose.
PCI guided by fractional flow reserve assessment may have yielded better outcomes in patients with less complex coronary anatomy, researchers say; others doubt the appropriateness of the subgroup analysis.