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August 28, 2021
Understanding the role of tau protein in Alzheimer's disease (AD) has led to new ways to diagnose it as well as the creation of medicines now in clinical trials to treat it.
August 27, 2021
Research from a large international effort shows that 20% of children with cancer who are infected with SARS-CoV-2 develop severe infections.
June 18, 2021
Research published today in the journal Cell is the first to establish how a specific gut bacterium, activated Bifidobacterium infantis EVC001 (B. infantis), influences immune system development in infants, and could thereby reduce the risk of allergic and autoimmune conditions later in life.
June 10, 2021
A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.
May 5, 2021
New insights on how hospitalized patients develop liver injury from taking different drugs A new study published in the British Journal of Clinical Pharmacology provides insights on how common hospitalized patients develop liver injury from taking different medications. When investigators analyzed the records of 156,570 hospitalized patients, they found 499 cases of drug-induced liver injury (DILI), for an incidence of 0.32%. Anti-infective agents, cancer medications, and nonsteroidal anti-inf...
May 1, 2021
Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants A Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center found that BK virus (BKV)-specific T cells from healthy donors were safe and effective as an off-the-shelf therapy for BKV-associated hemorrhagic cystitis (BKV-HC), a painful complication common after allogeneic stem cell transplants for patients with leukemia or lymphoma. The study was published ...
April 29, 2021
Researchers develop first 3D organoid models of the pancreas from human stem cells This year, more than 60,000 adults in the United States will be diagnosed with pancreatic cancer and, statistically, as few as 10 percent will survive five years after diagnosis, according to the American Cancer Society. Because pancreatic cancer is hidden deep within the body and often symptomless, its frequently diagnosed after the disease has progressed too far for surgical intervention and/or has spread throu...
April 21, 2021
Physical and mental health decline associated with more pronounced cognitive disengagement A recent study suggests that preserving physical and mental health helps older adults experiencing cognitive impairment stave off declines in cognitive engagement. We found that declines in physical and mental health were associated with more pronounced cognitive disengagement. The impact of declines in physical health was particularly pronounced for study participants who had more advanced cognitive impa...
April 8, 2021
Memory and executive function symptoms are valuable for predicting CTE pathology, suggests study Diagnosing Chronic Traumatic Encephalopathy (CTE) during life is crucial for developing therapies and for determining how common the disease is among individuals exposed to repetitive head impacts from contact sports, military service and physical violence. While the ability to diagnose CTE prior to death has remained elusive, researchers from Boston University School of Medicine (BUSM) for the firs...
April 7, 2021
Tibetan Plateau may Warm Faster in Future than Projected by Climate Models Written by AZoCleantechApr 7 2021 Over the last few decades, the Tibetan Plateau, called the roof of the world, has warmed up more quickly compared to the global average. Projected future warming of the Tibetan Plateau in the CMIP5 ensemble. The thick curves indicate the multi-model ensemble means and the shadings denote the 90% model intervals, derived from the raw model output. The dashed curves indicate the constrain...