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Study reveals how cells build 'mini-muscles' underneath their nucleus

Study reveals how cells build mini-muscles underneath their nucleus Research groups at the University of Helsinki uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile structures at the inner face of the cell membrane. This is the first time when such mini-muscles, also known as stress fibers, have been seen to emerge spontaneously through myosin-driven reorganization of the pre-existing actin filame...
Eteläuomen Läi Jaakko Lehtimaki Pekka Lappalainen Emily Henderson Hilife Institute Of Biotechnology University Of Helsinki

Study provides detailed insight into neural mechanisms underlying placebo effects

Study provides detailed insight into neural mechanisms underlying placebo effects A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individuals mindset, not to the drug itself. Understanding the neural mechanisms driving this placebo effect has been a longstanding question. A meta-analysis published in Nature Communications finds that placebo treatments to reduce pain, known as placebo analgesia, reduce pain-rel...
Ulrike Bingel Dianal Taylor Matthias Zunhammer Emily Henderson Nature Communications Affective Neuroscience Lab

Deep learning-based splice-AI can help predict the onset of Alzheimer's disease

Deep learning-based splice-AI can help predict the onset of Alzheimers disease Korea Brain Research Institute (KBRI, President Suh Pann-ghill) announced that the research team led by Dr. Jae-Yeol Joo discovered new cryptic splice variants and SNVs in PLCg1 gene of AD-specific models for the first time using Splice-AI. This research outcome was published in PNAS, a world-renowned academic journal. Prediction of Alzheimers Disease-Specific phospholipase c gamma-1 SNV by Deep Learning-Based Appro...
South Korea Suh Pann Ghill Jae Yeol Joo Emily Henderson Korea Brain Research Institute Brain Research Institute

Study indicates neural pathway that provides pain relief, reduces cravings for opioids

Study indicates neural pathway that provides pain relief, reduces cravings for opioids Researchers have discovered that there may be a new pathway in the brain that provides pain relief and reduces cravings for opioids. Over a third of the U.S. population suffers from chronic pain, with little to no reported relief from medication. Transcranial magnetic brain stimulation (TMS) is a noninvasive form of brain stimulation that may offer a new treatment option for these underserved members of our c...
Colleen Hanlon Julia Imperatore Emily Henderson Wake Forest School Of Medicine University Of South Carolina Department Of Psychiatry

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain

Neuroinvasiveness of SARS-CoV-2 shown by viral RNA and inflammation in the brain The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction. A new preprint on the bioRxiv* server d...
Liji Thomas Coronavirus Disease Covid 19 Sars Cov 2 Corona Virus Lewy Bodies Pituitary Gland

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Researchers identify a neural pathway critical to correcting behavioral errors

Researchers identify a neural pathway critical to correcting behavioral errors Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders. The teams research, published February 19 in Neuron, also suggests that neurostimulation of this brain pathway could provide an important mechanism for attention adjust...
Kevin Norman Hirofumi Morishita Emily Henderson Icahn School Of Medicine At Mount Sinai Development Institute Mindich Child Health

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows

Neurons activated by visual stimulus keep more active during subsequent sleep, study shows When you slip into sleep, its easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain. U-M researchers have been studying how memories associated with a specific sensory event are formed and stored in mice. In a study conducted prior to the coronavirus pandemic and recen...
United States Brittany Clawson Sara Aton Emily Henderson Um Department Of Molecular Nature Communications

IAR Systems introduces support for 64-bit Arm cores

IAR Systems introduces support for 64-bit Arm cores IAR Systems has announced that its C/C++ development toolchain IAR Embedded Workbench for Arm is now able to support 64-bit Arm cores including Arm Cortex-A35, Cortex-A53 and Cortex-A55. At a time when more applications are being based on 64-bit cores, specifically within low-power applications, deeply embedded and handheld devices, the Embedded Workbench provides customers with diverse microcontroller support as well a...
Stefan Skarin Arm Cortex A Embedded Workbench Embedded Software Software Development Tools ஸ்டீபன் ஸ்காரின்

Mice study finds altered brain connectivity after prolonged anesthesia

Mice study finds altered brain connectivity after prolonged anesthesia Prolonged anesthesia, also known as medically induced coma, is a life-saving procedure carried out across the globe on millions of patients in intensive medical care units every year. But following prolonged anesthesia--which takes the brain to a state of deep unconsciousness beyond short-term anesthesia for surgical procedures--it is common for family members to report that after hospital discharge their loved ones were not...
Rafael Yuste Michael Wenzel Emily Henderson Sciences At Columbia Columbia University Biological Sciences

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