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Group 3 innate lymphoid cells in intestinal health and disease

Group 3 innate lymphoid cells in intestinal health and disease
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Frontiers | The fecal microbiota from children with autism impact gut metabolism and learning and memory abilities of honeybees

Frontiers | The fecal microbiota from children with autism impact gut metabolism and learning and memory abilities of honeybees
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Adalimumab Biosimilar Effective, Safe for Inflammatory Bowel Disease Patients in China

This new research opens the door for further biological agent use in IBD therapy, helping to expand patients’ array of options when seeking IBD treatment in different countries.

Physiology and diseases of tissue-resident macrophages

Embryo-derived tissue-resident macrophages are the first representatives of the haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages originate from early yolk sac progenitors and are specified into tissue-specific subsets during organogenesis—establishing stable spatial and functional relationships with specialized tissue cells—and persist in adults. Resident macrophages are an integral part of tissues together with specialized cells: for instance, microglia reside with neurons in brain, osteoclasts reside with osteoblasts in bone, and fat-associated macrophages reside with white adipocytes in adipose tissue. This ancillary cell type, which is developmentally and functionally distinct from haematopoietic stem cell and monocyte-derived macrophages, senses and integrates local and systemic information to provide specialized tissue cells with the growth factors, nutrient recycling and waste removal that are critical for tissue growth, homeostasis and

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