The Danish Rheumatism Association gathers Denmark's largest choir for an (achy) joint howl of pain that expresses the reality of living with arthritis.
Developing depression after a diagnosis of rheumatoid arthritis substantially increased the risk for death over 10 years in a large Danish population study.
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Researchers have uncovered pathways involved in the body s response to glucocorticoid treatments and identified a novel biomarker that could be used to monitor how these drugs work in patients, according to a clinical study published today in
eLife.
A more reliable indicator of an individual s response to glucocorticoid drugs could be used to develop a clinically applicable test that could help tailor treatments and potentially minimise side-effects.
Glucocorticoids, such as cortisol, are a type of hormone with key roles in the body s response to stress. Glucocorticoid drugs are one of the most commonly prescribed treatments for a range of conditions, including for patients whose adrenal glands are unable to produce enough cortisol. The effects of glucocorticoids are complex, meaning the level of cortisol in the blood does not reliably reflect what is happening in the tissues. This makes it hard for medical professionals to know how to tailor treatments.