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DARPA to Build Virtual Data Scientist Assistants Through A I

DARPA to Build Virtual Data Scientist Assistants Through A I
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Wade shenVm programDefense advanced research projects agencyInformation innovation officeData driven discovery

New Tool Improves Classification of Inherited Disease Genes

New Tool Improves Classification of Inherited Disease Genes
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University of pennsylvaniaUnited statesSharonj diskinJung kimPathogenicity autoJo lynne rokitaDivision of cancer epidemiologyHealth informaticsNational institutes of healthDivision of neurosurgeryAmerican college of medical geneticsPerelman school of medicineNational cancer instituteIntramural researchChildren brain tumor networkJournal of the national cancer institute

Researchers develop new tool for better classification of inherited disease-causing variants

Researchers from Children s Hospital of Philadelphia (CHOP), the Perelman School of Medicine at the University of Pennsylvania, and the National Cancer Institute (NCI) of the National Institutes of Health have developed a new tool that allows scientists to annotate variant data from large-scale studies with clinically-focused classifications for risk of childhood cancer and other diseases. This new tool brings older applications in line with current guidelines and is available for use—for free—in the research community. The tool was described in a paper recently published in the journal Bioinformatics.

United statesUniversity of pennsylvaniaJung kimPathogenicity autoJo lynne rokitaSharonj diskinPerelman school of medicineAssociation for molecular pathologyAmerican college of medical geneticsHealth informaticsJournal of the national cancer instituteDivision of cancer epidemiologyChildren brain tumor networkDepartment of biomedicalNational cancer instituteNational institutes of health

Velsera and Flywheel Team up to Support Multimodal Imaging Genomics Research

Velsera and Flywheel Team up to Support Multimodal Imaging Genomics Research
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United statesBrian lassiterTravis richardsonVelsera jack digiovannaAdamc resnickData coordinating centerOffice of data science strategyCombining velseraFlywheel enterpriseData driven discoveryUnderstand downFlywheel core platformCoordinating centerData science strategyChief strategistFlywheel core

The GPCR Puzzle: New Research Reveals Molecular Origins of Function for a Key Drug Target

Scientists at St. Jude Children's Research Hospital, collaborating internationally, used data science, pharmacology, and structural details to explore at the atomic level how each amino acid in the adrenaline-binding receptor affects its activity when interacting with this natural ligand. They di

United kingdomUnited statesGeorgej pedersenMaria marti solanoZhaowen luoManbir sandhuFranziska heydenreichBrian kobilkaBriank kobilkaFranziskam heydenreichMichel bouvierM madan babuInstitute for researchStanford university school of medicineWellcome trust institutional strategic support fundDepartment of biochemistry