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Socioeconomic Disparities Associate With Epigenetics and Heart Failure Outcomes

Previously, Wendeโ€™s group assisted in a study that identified links between DNA methylation in all cause heart failure associated with the ability to use different metabolic fuels to maintain contractility, namely a decrease in oxidative metabolism.[2] An additional study from the group found molecular mechanisms specific to ischemic heart failure, which identified a key epigenetic regulator (i.e. EZH2) as likely having an active role in gene expression regulation involved in both metabolic a...
United States Marke Pepin Jacques Kpodonu Adamr Wende Kim Allan Williams Roxana Mehran

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