Due to its relatively high prevalence and recurrent nature, depression causes a major burden on healthcare systems, societies and individuals. Our objective was to investigate healthcare resource utilization and costs associated with treatment-resistant depression (TRD) compared with non-treatment-resistant depression in Finland. Of all patients aged 16–65 years and diagnosed with depression in Finland during 2004–2016, persons with TRD (N = 15,405) were identified from nationwide registers and matched 1:1 with comparison persons with depression who initiated antidepressant use but did not have TRD at the time of matching. TRD was defined as initiation of a third treatment trial after having failed two pharmacological treatment trials. Follow-up period covered 5 years after TRD or corresponding matching date (until end of 2018). Health care resource utilization was studied with negative binomial regression and costs of TRD (per patient per year) with gener
In the three months since the invasion of Ukraine by Russian forces on February 24, 2022, Direct Relief has emerged as one of the largest charitable providers of medical aid to Ukraine, delivering more than 650 tons (1.3 million pounds) of medicines and supplies and providing over $14.6 million in direct financial assistance to other […]
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Despite the substantial impact of the COVID-19 pandemic on patient care during 2020, the scientific advances in oncology continued, with 3,500 new drugs in the pipeline in 2020, up 75 percent since 2015. Oncologists worldwide report caseloads that are 26 to 51 percent lower than pre-pandemic levels, resulting in .
Operational Update: Infusions of Respiratory Support, PPE for Hospitals Continue
Prepped for departure from Direct Relief s warehouse, medical aid is staged on Thursday, Jan. 21, 2021, bound for health facilities across the globe. (Tony Morain/Direct Relief)
Over the past seven days, Direct Relief has shipped requested medical aid to 41 U.S. states and territories and 16 countries around the world, amounting to more than 10 million Defined Daily Doses of medication.
Operational activity remains high for California, where cases continue to break records week after week. This week, it became the first U.S. state to record a total of 3 million cases since the pandemic began.