Credit: ZZM/UZH
During the last 30 years, medical and dental research has attracted a large number of scientists and practitioners working on aspects of high medical relevance that involve a combination of genetic and tissue regeneration approaches. These developments in stem cell and tissue engineering have provided medical and dental researchers with new insights and given rise to new ideas as to how everyday clinical practice can be improved. Many research groups are dealing with questions like: How can we help injured tissues and organs heal? Can lost tissue be regenerated? How can we create solid protocols that apply across all stem cell therapies?
First Comprehensive Single-Cell Atlas of Human Teeth
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New machine learning method for designing more effective antibody drugs
Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs. This is because antibodies are extremely good at binding specifically to molecular structures according to the lock-and-key principle. Their use ranges from oncology to the treatment of autoimmune diseases and neurodegenerative conditions.
However, developing such antibody drugs is anything but simple. The basic requirement is for an antibody to bind to its target molecule in an optimal way. At the same time, an antibody drug must fulfil a host of additional criteria. For example, it should not trigger an immune response in the body, it should be efficient to produce using biotechnology, and it should remain stable over a long period of time.
AI-Based Technique Improves Development of Antibody Drugs
Written by AZoRoboticsApr 16 2021
The immune cells in human beings produce antibodies that fight more than just viruses and other microbes in the body.
Antibodies are being used as drugs. Image Credit: Shutterstock.
Now for several years, antibodies generated by biotechnology are also being used by the medical field as a form of drugs. The reason for this is that antibodies have an excellent ability to attach particularly to molecular structures in accordance with the lock-and-key principle.
Such antibodies are used in many fields, such as oncology and for treating neurodegenerative conditions and autoimmune diseases.
Credit: ETH Zurich
Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs. This is because antibodies are extremely good at binding specifically to molecular structures according to the lock-and-key principle. Their use ranges from oncology to the treatment of autoimmune diseases and neurodegenerative conditions.
However, developing such antibody drugs is anything but simple. The basic requirement is for an antibody to bind to its target molecule in an optimal way. At the same time, an antibody drug must fulfil a host of additional criteria. For example, it should not trigger an immune response in the body, it should be efficient to produce using biotechnology, and it should remain stable over a long period of time.
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