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 E-Mail IMAGE: Colorized scanning electron micrograph of an apoptotic cell (pink) heavily infected with SARS-COV-2 virus particles (green), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF). view more  Credit: National Institute of Allergy and Infectious Diseases/NIH, 2020 (CC0) A novel computational drug screening strategy combined with lab experiments suggest that pralatrexate, a chemotherapy medication originally developed to treat lymphoma, could potentially be repurposed to treat Covid-19. Haiping Zhang of the Shenzhen Institutes of Advanced Technology in Shenzhen, China, and colleagues present these findings in the open-access journal PLOS Computational Biology. With the Covid-19 pandemic causing illness and death worldwide, better treatments are urgently needed. One shortcut could be to repurpose existing drugs that were originally developed to treat other conditions. Computational methods can help identify such dru

Haiping zhangNational scienceShenzhen institutes of advanced technologyNational key researchDevelopment program of china under grant noShenzhen basic research fund under grantInnovation program for excellent young researchersTechnology major project under grant noNational science foundation of china under grantShenzhen institutesAdvanced technologyDevelopment programStrategic priorityTechnology major projectNational science foundationNational natural youth science foundation