Page 14 - Developmental Cell News Today

PHILADELPHIA-- A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. Developmental Cell, discovered that the protein encoded by GAS2 is crucial for maintaining the structural stiffness of support cells in the inner ear that normally help amplify incoming sound waves. They showed that inner ear support cells lacking functional GAS2 lose the...

In vitro models were created using stem cells from a patient with a rare gene mutation that affects myelination. The model showed that key aspects of this cell bundle were consistent with the disease.

Tiny 3D brain models could accelerate drug research for multiple sclerosis Tiny 3-D models that mimic vital aspects of the human nervous system have been developed in a step that could accelerate drug research for neurological conditions such as multiple sclerosis (MS). The millimetre-wide models - created using stem cells from human skin samples - will be used to study myelin, an insulating substance that helps nerve cells communicate with each other. Researchers say the models are the most na...

Tiny 3-D models that mimic vital aspects of the human nervous system have been developed in a step that could accelerate drug research for neurological conditions such as multiple sclerosis (MS).

Researchers discover elusive cell type in fish sensory organs One of the evolutionary disadvantages for mammals, relative to other vertebrates like fish and chickens, is the inability to regenerate sensory hair cells. The inner hair cells in our ears are responsible for transforming sound vibrations and gravitational forces into electrical signals, which we need to detect sound and maintain balance and spatial orientation. Certain insults, such as exposure to noise, antibiotics, or age, cause i...

 E-Mail Credit: Piotrowski Lab KANSAS CITY, MO--One of the evolutionary disadvantages for mammals, relative to other vertebrates like fish and chickens, is the inability to regenerate sensory hair cells. The inner hair cells in our ears are responsible for transforming sound vibrations and gravitational forces into electrical signals, which we need to detect sound and maintain balance and spatial orientation. Certain insults, such as exposure to noise, antibiotics, or age, cause inner ear hair...

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves How do we become a complex, integrated multicellular organism from a single cell? While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmanns recent work on the plant Arabidopsis thaliana has uncovered surprising answers. In a new study, published April 5 in Developmental Cell, led by Bergmann and postdoctoral...

 E-Mail IMAGE: A drawing series by artist Virginia Lopez-Anido that was inspired by research by her sister, Camila Lopez-Anido, a postdoctoral scholar at Stanford who studies cellular development in plants. view more  Credit: Virginia Lopez-Anido How do we become a complex, integrated multicellular organism from a single cell? While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmanns recent wo...

A new study from McGill, published recently in Developmental Cell, has made a significant advance in identifying how environmental information is transmitted by non-DNA molecules in the sperm.

A new study from McGill, published recently in