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Social risk factors 'heavily influence' racial disparities in cancer surgical care

Black Medicare beneficiaries who underwent elective cancer surgery had higher rates of mortality than their white counterparts, irrespective of neighborhood deprivation or dual eligibility status, according to study results.The findings, presented at Society of Surgical Oncology International 2022 Conference on Surgical Cancer Care, also showed a more pronounced effect of race among those with
United States Sidra Bonner Devin Mclaughlin Society Of Surgical Oncology International Society Of Surgical Oncology International Conference On Surgical Cancer Care
Source: healio.com

Immune cell parameters linked to therapeutic efficacy in advanced renal cell carcinoma

SAN FRANCISCO — Certain immune cell-related parameters appeared associated with efficacy of immune checkpoint inhibitors among patients with advanced or metastatic clear cell renal cell carcinoma, according to study results.“These immune cell parameters may represent novel predictive biomarkers for the response to nivolumab and/or nivolumab plus ipilimumab therapy in clear cell [renal
San Francisco United States Merck Serono Marc Oliver Grimm Devin Mclaughlin Astellas Pharma
Source: healio.com

Some men with prostate cancer may benefit from continued enzalutamide after progression

SAN FRANCISCO — Continued enzalutamide, after progression on the drug, in combination with docetaxel significantly extended PFS compared with placebo and docetaxel among men with metastatic castration-resistant prostate cancer, study results showed.Enzalutamide (Xtandi; Astellas, Pfizer), an androgen receptor antagonist, plus docetaxel also demonstrated an acceptable safety profile in the
San Francisco United States Enzalutamide Xtandi Devin Mclaughlin Astellas Pharma Axels Merseburger
Source: healio.com

Olaparib regimen benefits men with metastatic castration-resistant prostate cancer

SAN FRANCISCO  — The addition of olaparib to abiraterone acetate significantly extended radiographic PFS as first-line treatment for metastatic castration-resistant prostate cancer, according to an interim analysis of the randomized phase 3 PROpel study. The findings, presented at ASCO Genitourinary Cancers Symposium, showed men experienced the benefit regardless of homologous
San Francisco United States Devin Mclaughlin Fred Saad Astellas Pharma Myovant Sciences
Source: healio.com

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Individuals at high risk for multiple myeloma may benefit from novel screening technique

A novel high-sensitivity screening approach led to detection of monoclonal gammopathy of undetermined significance at significantly higher rates than conventional methods among people at high risk for multiple myeloma, study results showed.The findings, presented at ASH Annual Meeting and Exposition, confirmed a high prevalence of the multiple myeloma precursor condition among older adults and
Devin Mclaughlin Habib El Khoury Romina Sosa Binding Site Group Ltd Dana Farber Cancer Institute Iberia Romina Sosa
Source: healio.com

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