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Compound Map provides Foundation for SARS-CoV-2 Inhibitors Discovery

Apr 15 2021 Read 7 Times A new international study(1) has provided a template for how to develop directly-acting antivirals with novel modes of action, that would combat COVID-19 by suppressing the SARS-CoV-2 viral infection. The study focused on the macrodomain part of the Nsp3 gene product that SARS-CoV-2 uses to suppress the host cell’s natural antiviral response. This part of the virus’s machinery, also known as Mac1, is essential for its reproduction: previous studies have shown that v...
United Kingdom University Of Oxford Structural Biology Consortium University Of California San Francisco Diamond Light Source Biology Consortium

£12m partnership to help energy systems transition to net zero pollution by 2050 | Imperial News

07 April 2021 Imperial, Shell and Diamond Light Source are launching an EPSRC-funded Programme on materials and processes for the energy transition. The EPSRC Prosperity Partnership, known as InFUSE, will examine how technologies like batteries, electric vehicles, chemical production, and carbon capture and storage (CCS) can be improved by understanding interfaces in these systems, enhancing sustainability and enabling a transition to a green economy. Transitioning to renewable, sustainabl...
United Kingdom City Of Mary Ryan Sinead Lynch Kwasi Kwartengbusiness Kwasi Kwarteng

First images of cells exposed to COVID-19 vaccine reveal native-like Coronavirus spikes

Credit: University of Southampton New research has for the first time compared images of the protein spikes that develop on the surface of cells exposed to the Oxford-AstraZeneca vaccine to the protein spike of the SARS-CoV-19 coronavirus. The images show that the spikes are highly similar to those of the virus and support the modified adenovirus used in the vaccine as a leading platform to combat COVID-19. The SARS-CoV-2 virus, which causes COVID-19, has a large number of spikes sticking out o...
Peijun Zhang Sarah Gilbert Max Crispin Teresa Lambe University Of Southampton University Of Oxford

Unilever and Lubrizol green R&D projects snap up share of £75m UK funding

Unilever and Lubrizol green R&D projects snap up share of £75m UK funding Content by subject If you already have an account please use the link below to sign in. If you have any problems with your access or would like to request an individual access account please contact our customer service team. Unilevers Materials Innovation Factory in Liverpool | Credit: Unilever Winners of £75m public-private funding round for innovative technologies announced as government faces flak for effective cut ...
City Of United Kingdom Joe Marshall Richard Slater Kwasi Kwarteng United Kingdom Research

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'Little Foot' skull x-rayed in Didcot Diamond lab

A PRICELESS fossil of the 3.67-million -year-old ‘Little Foot’ skull was flown from South Africa to a lab near Didcot. With the help of an X-ray, scientists at the British research facility Diamond Light Source, were able to see some microscopic details in the ancient remains that could help unravel key clues to the origins of modern humans. The X-ray work from June 2019 is highlighted in a new paper in e-life published this week which reveals new information about evolution and human...
South Africa United Kingdom Sterkfontein Caves Dominic Stratford Ron Clarke Little Foot

New Tech Allows First Glimpse of Human Ancestor's Life

Copyright Diamond Light Source Ltd  In June 2019, an international team brought the complete skull of the 3.67-million-year-old Little Foot Australopithecus skeleton, from South Africa to the UK and achieved unprecedented imaging resolution of its bony structures and dentition in an X-ray synchrotron-based investigation at the UKs national synchrotron, Diamond Light Source. The X-ray work is highlighted in a new paper in e-Life, published Mar. 2 focusing on the inner craniodental features of ...
South Africa United Kingdom Sterkfontein Caves Dominic Stratford Thomas Connolley Ron Clarke

X-Rays Reveal Secrets of Little Foot's Skull - Archaeology Magazine

OXFORD, ENGLAND— BBC News reports that the skull of “Little Foot” traveled from South Africa to Britain, where it was examined at Diamond Light Source with synchrotron X-ray imaging technology. Ron Clarke of the University of the Witwatersrand explained that the nearly complete remains of this possible early human ancestor were discovered in the 1990s in South Africa’s Sterkfontein Caves, dated to 3.67 million years ago, and identified as Australopithecus prometheus. Little Foot’s an...
United Kingdom Ron Clarke University Of Cambridge Little Foot Scan South Africa Diamond Light Source

Top UK Scientists Helped China Develop Nuclear Weapons Tech: Report

3 Mar 2021 Scientists from at least thirty-three universities in the United Kingdom have worked with Chinese military researchers on the development of nuclear weapons, an investigation has claimed. Top academics, including those at the universities of Cambridge, Edinburgh and Manchester, have reportedly worked alongside researchers at China’s top nuclear weapons research institution, the Chinese Academy of Engineering Physics (CAEP). According to The Telegraph, academics from at least thirt...
United States United Kingdom City Of Radomir Tylecote Charles Lieber Charles Parton

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