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C goes beyond to reduce the risk of cardiovascular death for adults with type two diabetes and known heart disease and guardians may help you lose some weight. serious side effects, including ketoacidosis that may be fatal. dehydration can lead to sudden worsening of kidney function and genital yeast or urinary tract infections, a rare life threatening bacterial infection in the skin of the perineum could occur. stop taking guardians and call your doctor right away. if you have symptoms of this ...