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Researchers evaluated the impact of double BNT162b2 messenger ribonucleic acid (mRNA) vaccination in recognition of SARS-CoV-2 variants of concern.

SAN FRANCISCO, Aug. 09, 2022 -- Olema Pharmaceuticals, Inc. , today announced the advancement of OP-1250, a complete estrogen receptor antagonist and a selective ER degrader , into Phase 2... | August 9, 2022

A clinical trial to test whether three proven smoking cessation treatments could also reduce alcohol intake found no differences between the medications, but the rates of behavior change for alcohol consumption and smoking were high in all treatment groups. Results suggest these medications could play an important role to reduce alcohol use and smoking at the same time. Unexpectedly, nicotine replacement therapy performed as well as the prescription drugs varenicline and cytisine.

In a new study, researchers systematically mapped the surface proteins on human leukocytes to examine interactions between their cell-surface proteomes and develop a physical wiring diagram encapsulating the diversity of surface protein architectures found across all major subsets of leukocytes.

In a new study, investigators examined if SARS-CoV-2 Omicron BA.2 breakthrough infection in triple vaccinated individuals boosts Omicron BA.4/BA.5 and BA.2.12.1 cross-neutralization.

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

Researchers develop a genetically modified airway organoid system, which overcomes challenges related to natural variations in ACE2 levels