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Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Investigators have discovered the mechanisms underlying a T-cell receptor's immunosuppressive function, according to a study published Nature Immunology, findings that may provide insight into the development of novel precision therapeutics for chronic diseases, including cancer.
Hui Zhang Emily Henderson Mesulam Center Roberth Lurie Comprehensive Cancer Center Division Of Biostatistics Northwestern University

A sugar-studded protein could be key to stopping Alzheimer's disease progression, finds study

In a bit of "reverse engineering" research using brain tissues from five people who died with Alzheimer's disease, Johns Hopkins Medicine researchers say they discovered that a special sugar molecule could play a key role in the development of Alzheimer's disease.
United States Anabel Gonzalez Gil Alvarenga Ronald Schnaar John Jacob Abel Emily Henderson Johns Hopkins University School Of Medicine

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Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

In a recent study posted to the medRxiv* preprint server, investigators in Singapore showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection elicited broadly specific virus-selective nasal resident CD8 and CD4 T cells.
Corona Borealis Studio Image Credit Coronavirus Disease Covid 19 Ars Cov 2 Ngiotensin Converting Enzyme 2 Covid 19

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

In a recent study published in the journal Cell, researchers demonstrated that antibodies generated due to breakthrough infection (BTI) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron in vaccinated individuals could neutralize all VOCs.
Aimee Molineux Neha Mathurmay Neha Mathur Coronavirus Disease Covid 19 Ngiotensin Converting Enzyme 2 Covid 19

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