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Study underscores need for primary prevention in advanced breast cancer

While regular screenings may decrease the chance of diagnosis of advanced breast cancer in some women and lead to a 20% reduction in breast cancer mortality, other women will be diagnosed with advanced breast cancer despite screening at regular intervals.
United States Karla Kerlikowske University Of California San Francisco Medical Center Breast Cancer Surveillance Consortium American Joint Committee On Cancer California San Francisco Medical

Novel stem cell treatment could revolutionize liver disease management

Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire need for new forms of treatment.
United States Boston University Valerie Gouon Evans Boston University Liver Biologist Program Boston Medical Center Boston University Chobanian

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Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.
United States Kateryna Kon Shutterstock Sprague Dawley National Institute Of Health National Institute On Drug Abuse Drug Supply Program

IDEA trial: Skipping radiotherapy safe for younger postmenopausal patients with early-stage breast cancer

Almost all postmenopausal patients aged 50-69 years with stage I hormone receptor (HR)-positive breast cancer and low scores on a common genetic test who opted out of adjuvant radiotherapy were disease free five years after surgery, according to results from the IDEA clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.
San Antonio United States Lawrencew Davis Reshma Jagsi Emory University School Of Medicine Doris Duke Foundation

Study challenges link between proton pump inhibitors and kidney disease risk

A study in Scientific Reports investigates the association between proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RA) use on chronic kidney disease (CKD) risk.
Observational Health Data Sciences Observational Medical Outcomes Partnership Common Data Model National Sample Cohort National Health Insurance Service Scientific Reportsstudy Iryna Imago

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