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SARS-CoV-2 neutralizing antibodies discovered in a 20-year-old human antibody library

In an article published in the open-access journal Advance Engineering, a multinational team of researchers reported the selection and characterization of 3 potent SARS-CoV-2 antibodies - S-E6, S-B8, and S-D4 - from a pre-COVID-19 human combinatorial antibody library that was established 20 years ago.
Susha Cheriyedath Human Antibody Library Constructed Decades Neutralizing Antibodies Image Credit Corona Borealis Studio Advance Engineering

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SARS-CoV-2 variants neutralized by camel nanobodies

Researchers from the US recently isolated two VHH nanobodies - 7A3 and 8A2 - from dromedary camels (Camelus dromedaries) using phage display. These nanobodies were found to have a high affinity for the spike RBD and broad neutralization abilities against SARS-CoV-2 and its variants.
South Africa United Kingdom Susha Cheriyedath Emergency Use Authorization Coronavirus Disease Covid 19 Ars Cov 2

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the COVID-19 vaccine was not associated with severe disease flares in patients with rheumatic diseases.
Emily Henderson Professor At Mcgill University Department Of Medicine American College Of Rheumatology American College Associate Professor Mcgill University

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