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BUB1 protein and its kinase activity may regulate EGFR activation

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization."
United States Megan Craig Corey Speers Shyam Nyati Alnawaz Rehemtulla Mukeshk Nyati

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Combination therapy shows promise in treating advanced ER+ breast cancer

Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, PhD, shows promise in using a combination of estrogen and a PARP inhibitor (a drug that suppresses DNA damage repair), to treat this type of cancer.
United States Megan Craig Toddw Miller American Association For Cancer Research Clinical Cancer Research Dartmouth Cancer Center

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