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MyJournals.org - Science - 'IJMS, Vol. 24, Pages 7356: Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking' (International Journal of Molecular Sciences)

MyJournals.org - Science - IJMS, Vol. 24, Pages 7356: Structural Insights into M1 Muscarinic Acetylcholine Receptor Signaling Bias between Gαq and β-Arrestin through BRET Assays and Molecular Docking (International Journal of Molecular Sciences)
G Alpha Q Eta Arrestin

MyJournals.org - Science - 'IJMS, Vol. 24, Pages 7265: Derrone Targeting the TGF Type 1 Receptor Kinase Improves Bleomycin-Mediated Pulmonary Fibrosis through Inhibition of Smad Signaling Pathway' (International Journal of Molecular Sciences)

MyJournals.org - Science - IJMS, Vol. 24, Pages 7265: Derrone Targeting the TGF Type 1 Receptor Kinase Improves Bleomycin-Mediated Pulmonary Fibrosis through Inhibition of Smad Signaling Pathway (International Journal of Molecular Sciences)
Leomycin Mediated

MHRA research evaluates two different approaches to cancer therapies

The report 'Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue', published in the PLOS ONE journal, highlights MHRA research which showed that genetic engineering of antibodies used to activate and support the immune system against cancer leads to improvements in their reliability and effectiveness.
United Kingdom Emily Henderson Sandras Diebold Henry Stennett Research Information Cancer Research United Kingdom

New treatment pathway identified for patients with idiopathic nephrotic syndrome

With funding from charity Kidney Research UK, Dr Carl May from Bristol Medical School and his team have identified a new treatment pathway for patients with non-genetic (idiopathic) nephrotic syndrome (INS), targeting a still unknown factor that causes the progression towards kidney failure.
City Of United Kingdom Emily Henderson David Hughes Kidney Research United Kingdom University Of Bristol

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