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Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

A vaccine design approach that could protect against new variants of SARS-CoV-2, the virus that causes COVID-19, but also potentially protects against other coronaviruses is one step closer to reality as a result of Penn State College of Medicine research.
G Thomas Passananti Yashavantha Vishweshwaraiah Nikolay Dokholyan Emily Henderson Centers For Disease Penn State College Of Medicine

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.
Endothelial Dysfunction Potential Mechanisms Possible Therapeutic Image Credit Genomics Industry Focus Coronavirus Disease Covid 19

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).
International Journal Of Molecular Sciences International Journal Molecular Sciences Coronavirus Disease Covid 19 Covid 19 Vitamin D

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Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to theย bioRxiv*ย preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.
Brighton And Hove United Kingdom World Health Organization Central Africa Dotted Yeti Genomics Industry Focus

High immune protein levels predict both heart failure and death

For years, cardiologists have zeroed in on a hormone called BNP as a gold standard to determine if patients with heart failure are at risk of severe illness or death. It's released by the heart in response to when the cardiac tissue stretches due to pressure.
United States Salim Hayek Arshed Ali Quyyumi Emily Henderson Emory Clinical Cardiovascular Institute University Of Michigan Health Frankel Cardiovascular Center

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

A new study evaluated the current research on incidences of hypertension, new-onset diabetes mellitus, and dyslipidemia as possible sequelae of coronavirus disease 2019 (COVID-19).
Chompoo Suriyo Shutterstock Public Health International Journal Of Environmental Research International Journal Environmental Research New Onset Diabetes Mellitus

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